Spatio-temporal encoding and decoding in cell signaling

March, 18th 2021, Online


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9:00 am








Session 1: Calcium signaling

Chair person: Geneviève DUPONT, Université libre de Bruxelles, Belgique



Invited talks

9:15 am


Spatio-temporal dynamics of calcium signaling in tiny subcellular domains: the case of astrocyte processes - Hugues BERRY, Inria Grenoble Rhône-Alpes, équipe-projet Beagle

9:55 am


Amplitude versus frequency coding in calcium oscillations - Ursula KUMMER, COS Heidelberg, Modeling of Biological Processes



Selected short talks

10:35 am


Simulation of astrocytic calcium signals in microscopy images based on kinetic models – Anaïs BADOUAL, Inria Rennes, France

10:47 am


Three-dimensional model of sub-plasmalemmal Ca2+ microdomains evoked by the interplay between ORAI1 and InsP3 receptors – Diana Gil Montoya, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

11:00 am


Short break



Session 2: Signaling and decision making 

Chair person: Laurence CALZONE, Institut Curie, Paris, France



Invited talks

11:10 am


Decoding and Re-encoding MAPK Fate Decision Signaling - Olivier PERTZ, University of Bern, Institute of Cell Biology

11:50 am


A positive feedback loop in apoptosis to explain heterogeneity in cell response to cancer drugs - Madalena CHAVES, Inria Sophia Antipolis - Méditerranée, équipe-projet Biocore



Selected short talks

12:30 pm


Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying its signaling pathway usage – Olivier Destaing, Institute for Advanced Biosciences, Grenoble, France

12:42 pm


Modeling cell fate specification during early embryonic development in mouse – Didier Gonze, Université Libre de Bruxelles, Belgium

12:54 pm


Chemotaxis impact on a Turing reaction-diffusion system – Camille Fraga Delfino Kunz, Frankfürt Institute for Advanced Studies, Frankfürt, Germany

1:06 pm


Detection and tracking of collective signalling – Maciej Dobrzynski, Institute of Cell Biology, University of Bern, Switzerland




1:20 pm


Lunch break









Session 3: GPCR signaling

Chair person: Frédérique CLEMENT, INRIA-Saclay, France



Invited talk

2:30 pm


Role of kinetics and trafficking in GPCR-mediated signaling - Eric REITER, UMR Physiologie de la Reproduction et des Comportements, équipe BIOS (Biologie et bioinformatique des systèmes de signalisation)



Selected short talks

3:10 pm


Dynamics and cell-specific activity of signaling pathways are altered in neurons of Parkinsonian mice – Nicolas Gervasi, Collège de France, Paris, France

3:22 pm


Quantitative fret and stoichiometry measurements with Quanti-FRET – Aurélie Dupont, LIPhy, Grenoble, France

3:34 pm


Kinetic control of the temporal dynamics of a RhoA signaling cascade – Serena Prigent-Garcia, IBPS – LBD, Paris, France

3:46 pm


Short break






Session 4: Onset and propagation of oscillations in signaling

Chair person: Laurent COMBETTES, Inserm, Orsay, France



Selected short talk

4:00 pm


cAMP bursts control T cell directionality by actinmyosin cytoskeleton remodelling – Morgane Simao, Institut Cochin, Paris, France



Invited talks

4:12 pm


Modeling the onset of periodic and excitable dynamics in signaling motifs - Jacques-Alexandre SEPULCHRE, Institut de Physique de Nice

4:52 pm


Short break

5:05 pm


Autonomous oscillations of confined epithelia: a dance-based rangefinder - Joseph D’ALESSANDRO, Institut Jacques Monod, équipe Adhésion cellulaire et mécanique




5:45 pm


Awards for the best short communications, concluding remarks


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