Nuclear regulation of the UPR.
Anna Babour. Inserm, Paris, France
BAX inhibitor 1 protects against pancreatic beta cell death and metabolic disorders.
Marina Blanc. Centre Méditerranéen de Médecine Moléculaire, Nice, France
Targeting unfolded protein response to resolve protein aggregates accumulation in oculopharyngeal muscular dystrophy. Alexis Boulinguiez, Institut de Myologie, Paris, France
RTCB Phospho-tyrosine code during endoplasmic reticulum stress.
Federica Grazia Centonze. INSERM U1242, Université de Rennes, Rennes, France
The ER-resident FKBP7: a new candidate for the endoplasmic reticulum to cytosol signaling (ERCYS) pathway?
Luce Dreno. Inserm UMR981 - Gustave Roussy, Villejuif, France
Evidences for a role of Phosphoinositides metabolism in cell-cell communication at plasmodesmata.
Gwennogan Dubois. RDP - Laboratoire de Reproduction et développement des Plantes, Lyon, France
Functional dissection of the retrograde Shiga toxin trafficking inhibitor RETRO-2.
Alison Forrester. Institut Curie Paris, France
ORP5 and ORP8 regulate lipid droplets (LD) biogenesis at ER-mitochondria contact sites.
Valentin Guyard. Institute for Integrative Biology of the Cell, Gif-sur-Yvette, France
Inhibition of Inositol-Requiring Enzyme 1 Alpha signaling sensitives Hepatocellular Carcinoma to Sorafenib.
Marion Janona. C3M INSERM U1065, Nice, France
IRE1 RNase controls CD95 signalling.
Elodie Lafont. INSERM U1242, CLCC Eugène Marquis, Université de Rennes, Rennes, France
Dymeclin, the protein defective in DMC syndrome and SMC dysplasia is an effector of RAB33B involved in Golgi-ER trafficking
Sophie Lebon. Neurodiderot - Inserm U1141, Paris, France
IRE1a and STIM1 regulate INFb secretion in dendritic cells.
Lucie Maisonneuve. INEM - INSERM U1151, Paris, France
The role of HSPA5 and the unfolded protein response in group 3 medulloblastoma
Liliana Mirabal-Ortega. Institut Curie, Université de Paris, Orsay, France (also presented online)
Exploring the potential of the ER as a therapeutic target site against amyloid-beta production.
Pierre Parutto. UK Dementia Research Institute at University of Cambridge, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK (also presented online by Gupta)
A novel blood brain barrier-permeable IRE1 kinase inhibitor sensitizes glioblastoma to chemotherapy in mice.
Diana Pelizzari Raymundo. INSERM U1242, Université de Rennes, Rennes, France., Rennes, France (also presented online)
Increasing triacylglycerols and lipid storage by unsaturated lipids reduces ER stress and protects renal proximal tubules from saturated lipids.
Albert Perez-Marti. Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany (also presented online)
Role of the Unfolded Protein Response during Shigella infection of epithelial cells.
Ilaria Pontisso. ENS Paris-Saclay, Gif-sur-Yvette, France
Role of endoplasmic reticulum inter-organelle contacts in neuronal endosomal traffic.
Monica Quinones-Frias. Brandeis University, Waltham, USA (also presented online)
Role of Spastin (SPG4) in mitochondrial-ER contact sites.
Amélie Raby. Genethon, Evry, France
Live staining of the endoplasmic reticulum redefines haematopoietic cells’ hierarchy.
Kevin Rouault-Pierre. Barts Cancer Institute, Queen Mary University of London, London, UK
The role of VAPA-mediated membrane contact sites during collective cell migration.
Hugo Siegfried. Institut Jacques Monod, CNRS UMR7592, Université Paris Diderot, Paris, France
Endoplasmic Reticulum Membrane Contact Sites tune exosome secretion by modulating multivesicular body maturation and transport.
Frederik Verweij. IPNP INSERM U1266 / Utrecht University, Paris, France
Novel FRET imaging method for the live-cell study of protein-protein interactions at the endoplasmic reticulum membrane.
Dounia Zamiati. Institut de Chimie Physique- Université Paris-Saclay, Orsay, France
UFL1-dependent regulation of endoplasmic reticulum stress and death receptor signalling in triple-negative breast cancer cells.
Xingchen Zhou. Inserm 1242, Rennes, France
Transmembrane zipper of polar residues modulates the activation of the protein kinase IRE1.
Juan Cruz Almada. Universidad Nacional de Rosario-Argentine National Research Council-CONICET, Rosario, Argentina
Uncovering the pro-cancerous functions of PDI and PDI-like proteins in the cytosol of cancer cells.
Faiza Almaterat. Department of life sciences. Ben Gurion university of the Negev, Beer Sheva, Israel
Involvement of IRE1α, a mediator of endoplasmic reticulum stress, in the DNA damage response.
Alice Blondel. INSERM U1242, Université de Rennes, Rennes, France., Rennes, France
Respiratory viral infection and the role of endoplasmic reticulum stress in airway epithelial cells.
Kirsty Bradley. University of Sheffield, Sheffield, UK
Using a Man2C1 knockdown mouse line for monitoring er associated degradation (ERAD) of glycoproteins.
Isabelle Chantret. INSERM Unité 1149, Paris, France
Dissecting endoplasmic reticulum unfolded protein response (UPRER) in Echinococcus sp. through IRE-bZIP signalling.
Andrea Cumino. Conicet - Universidad Nacional de Mar del Plata, Mar del Plata, Argentina
CMT2A-linked MFN2 mutant promotes mitochondrial hyperfusion and altered ER-mitochondria associations via mitol mediated ubiquitylation and degradation of DRP1.
Rajdeep Das. Saha Institute of Nuclear Physics, Kolkata, India
Investigating the role of unfolded protein response in megakaryocyte maturation.
Mifra Faiz. University of Otago, North Dunedin, New Zealand
Secreted AGR2 and cancer cell proliferation: role of p21CIP1.
Delphine Fessart. INSERM U1218, Bordeaux, France
Exploring the potential of the ER as a therapeutic target site against amyloid-beta production.
Karnika Gupta. DRI, Cambridge, Cambridge, UK
Sleep apnea in idiopathic pulmonary fibrosis: a molecular investigation in an experimental model of fibrosis and intermittent hypoxia.
Liasmine Haine. Université Sorbonne Paris Nord, Bobigny, France
Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex.
Yoel Klug. Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
Endoplasmic reticulum morphologen reticulon 4 determines axonal plasticity by speed limiting luminal transport.
Tasuku Konno. UK Dementia Research Institute, University of Cambridge, Cambridge, UK
Using semantic network analysis to profile proteostasis evolution.
Thodoris Koutsandreas. Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, Athens, Greece
The role of HSPA5 and the unfolded protein response in group 3 medulloblastoma
Liliana Mirabal-Ortega. Institut Curie, Université de Paris, Orsay, France
Towards a pan-cancer atlas of endoplasmic reticulum stress network.
Mohammad Amin Moosavi. Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
A neuron within a neuron: dissecting axonal ER structure-function in Drosophila.
Cahir O'Kane. University of Cambridge, Cambridge, UK
A novel blood brain barrier-permeable IRE1 kinase inhibitor sensitizes glioblastoma to chemotherapy in mice.
Diana Pelizzari Raymundo. INSERM U1242, Université de Rennes, Rennes, France., Rennes, France
Increasing triacylglycerols and lipid storage by unsaturated lipids reduces ER stress and protects renal proximal tubules from saturated lipids.
Albert Perez-Marti. Institute of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany
Role of endoplasmic reticulum inter-organelle contacts in neuronal endosomal traffic.
Monica Quinones-Frias. Brandeis University, Waltham, USA
Inhibiting IRE1α /XBP1 activity enhances the chemotherapeutic effects in both in vitro and in vivo mice syngeneic models of colorectal Cancer.
Marveh Rahmati. Tehran University of Medical Scienses, Tehran, Iran
ERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape.
Miguel Sanchez-Alvarez. CNIC, Madrid, Spain
NNC-55-0396 activates the UPR and calcium signaling to induce glioblastoma cell death.
Anna Visa. IRB Lleida, Lleida, Spain